HNF4 alpha/gamma 抗体 (acLys79, acLys127)
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Quick Overview for HNF4 alpha/gamma 抗体 (acLys79, acLys127) (ABIN7228950)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys79, acLys127
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原理
- HNF-4α/γ (Acetyl Lys127/79) Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of HNF-4α/γ when Acetyl occurs at Lys127/79(human/mouse) or Lys127(rat).
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human HNF-4alpha/gamma (Acetyl Lys127/79) protein at AA range: 127 (HNF-4alpha) /79 (HNF-4gamma)
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亚型
- IgG
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anti-HNF4 alpha/gamma antibody
适用: 人, 小鼠, 大鼠 WB, IHC, IC, IF 宿主: 兔 Polyclonal unconjugated
anti-HNF4 alpha/gamma (Internal Region) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HNF4 alpha/gamma (AA 91-140) antibody适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- HNF4 alpha/gamma
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别名
- HNF-4alpha/gamma
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背景
- Rabbit Anti-HNF-4α/γ (Acetyl Lys127/79) Polyclonal Antibody,Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14 Hepatocyte nuclear factor 4-gamma, HNF-4-gamma, Nuclear receptor subfamily 2 group A member 2(TCF-14, Transcription factor HNF-4,The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. HNF4A may play a role in development of the liver, kidney, and intestines. Mutations in HNF4A have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of HNF4A results in multiple transcript variants encoding several different isoforms. HNF4A (Hepatocyte Nuclear Factor 4 Alpha) is a Protein Coding gene. Diseases associated with HNF4A include Mody, Type I and Fanconi Renotubular Syndrome 4, With Maturity-Onset Diabetes Of The Young. Among its related pathways are Type II diabetes mellitus and Mesodermal Commitment Pathway.,HNF-4α/γ
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分子量
- observerd band 55kDa
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基因ID
- 3172
抗原
-
