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MLL4 抗体 (AA 1060-1140)

This 兔 多克隆 anti-MLL4 antibody specifically detects MLL4 in IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7229698
发货至: 中国
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Quick Overview for MLL4 抗体 (AA 1060-1140) (ABIN7229698)

抗原

See all MLL4 抗体
MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

适用

  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 4
  • 2

克隆类型

  • 4
  • 2
多克隆

标记

  • 6
This MLL4 antibody is un-conjugated

应用范围

  • 5
  • 3
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1060-1140

    原理

    MLL4 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of MLL4 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human MLL4 protein at AA range: 1060-1140

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

    别名

    MLL4

    背景

    Rabbit Anti-MLL4 Polyclonal Antibody,Histone-lysine N-methyltransferase 2B , Lysine N-methyltransferase 2B, Myeloid/lymphoid or mixed-lineage leukemia protein 4, Trithorax homolog 2, WW domain-binding protein 7, WBP-7,KMT2B (Lysine Methyltransferase 2B) is a Protein Coding gene. Diseases associated with KMT2B include Dystonia 28, Childhood-Onset and Spindle Cell Sarcoma. Among its related pathways are Chromatin organization and Lysine degradation. KMT2B encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. KMT2B is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for KMT2B, however, the full length nature of the shorter transcript is not known.,MLL4

    分子量

    observerd band 298kDa

    基因ID

    9757

    UniProt

    Q9UMN6

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effect
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