MLL4 抗体 (AA 1060-1140)
Our Local Distributor
北京 101111
Quick Overview for MLL4 抗体 (AA 1060-1140) (ABIN7229698)
抗原
See all MLL4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1060-1140
-
原理
- MLL4 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of MLL4 protein
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
免疫原
- Synthesized peptide derived from part region of human MLL4 protein at AA range: 1060-1140
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))
-
别名
- MLL4
-
背景
- Rabbit Anti-MLL4 Polyclonal Antibody,Histone-lysine N-methyltransferase 2B , Lysine N-methyltransferase 2B, Myeloid/lymphoid or mixed-lineage leukemia protein 4, Trithorax homolog 2, WW domain-binding protein 7, WBP-7,KMT2B (Lysine Methyltransferase 2B) is a Protein Coding gene. Diseases associated with KMT2B include Dystonia 28, Childhood-Onset and Spindle Cell Sarcoma. Among its related pathways are Chromatin organization and Lysine degradation. KMT2B encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. KMT2B is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for KMT2B, however, the full length nature of the shorter transcript is not known.,MLL4
-
分子量
- observerd band 298kDa
-
基因ID
- 9757
-
UniProt
- Q9UMN6
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effect
抗原
-