HEXB 抗体 (AA 450-530)
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北京 101111
Quick Overview for HEXB 抗体 (AA 450-530) (ABIN7221476)
抗原
See all HEXB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 450-530
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原理
- Hexb Polyclonal Antibody
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特异性
- Hexb Polyclonal Antibody detects endogenous levels of Hexb protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Hexb at AA range: 450-530
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亚型
- IgG
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anti-Hexosaminidase B (Beta Polypeptide) (HEXB) (AA 122-311) antibody
HEXB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase B (Beta Polypeptide) (HEXB) (AA 315-456) antibodyHEXB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase B (Beta Polypeptide) (HEXB) (AA 294-435) antibodyHEXB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase B (Beta Polypeptide) (HEXB) (AA 101-217) antibodyHEXB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase B (Beta Polypeptide) (HEXB) (C-Term) antibodyHEXB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase B (Beta Polypeptide) (HEXB) (AA 381-556) antibodyHEXB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase B (Beta Polypeptide) (HEXB) (C-Term) antibodyHEXB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hexosaminidase B (Beta Polypeptide) (HEXB) antibodyMicroarray verified HEXB 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB461847 unconjugated
anti-Hexosaminidase B (Beta Polypeptide) (HEXB) antibodyMicroarray verified HEXB 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB220161 unconjugated
anti-Hexosaminidase B (Beta Polypeptide) (HEXB) (AA 100-216) antibodyHEXB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- HEXB (Hexosaminidase B (Beta Polypeptide) (HEXB))
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别名
- Hexb
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背景
- Rabbit Anti-Hexb Polyclonal Antibody,HEXB, HCC7, Beta-hexosaminidase subunit beta, Beta-N-acetylhexosaminidase subunit beta, Hexosaminidase subunit B, Cervical cancer proto-oncogene 7 protein, HCC-7, N-acetyl-beta-glucosaminidase subunit beta,Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for HEXB.,Beta-hexosaminidase subunit beta
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分子量
- observerd band 63kDa
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基因ID
- 3074
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UniProt
- P07686
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途径
- Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
抗原
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