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HCK 抗体 (pTyr521)

The 兔 多克隆 anti-HCK antibody (ABIN7221456) specifically detects HCK in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7221456
发货至: 中国
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Quick Overview for HCK 抗体 (pTyr521) (ABIN7221456)

抗原

See all HCK 抗体
HCK (Hemopoietic Cell Kinase (HCK))

适用

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  • 21
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 87
  • 8
  • 1

克隆类型

  • 79
  • 17
多克隆

标记

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  • 2
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  • 1
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This HCK antibody is un-conjugated

应用范围

  • 78
  • 42
  • 21
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Western Blotting (WB), ELISA
  • 抗原表位

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    • 2
    • 2
    • 2
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    • 1
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    • 1
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    pTyr521

    原理

    Hck (phospho Tyr521) Polyclonal Antibody

    特异性

    Phospho-Hck (Y521) Polyclonal Antibody detects endogenous levels of Hck protein only when phosphorylated at Y521.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Hck Phospho-Tyr521

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    HCK (Hemopoietic Cell Kinase (HCK))

    别名

    Hck

    背景

    Rabbit Anti-Hck (phospho Tyr521) Polyclonal Antibody,HCK, Tyrosine-protein kinase HCK, Hematopoietic cell kinase, Hemopoietic cell kinase, p59-HCK/p60-HCK, p59Hck, p61Hck,The HCK proto-oncogene, Src family tyrosine kinase encoded by HCK is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.,Tyrosine-protein kinase HCK

    分子量

    observerd band 60kDa

    基因ID

    3055

    UniProt

    P08631

    途径

    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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