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ATRX 抗体 (AA 80-160)

This 兔 多克隆 anti-ATRX antibody specifically detects ATRX in ELISA 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7223298
发货至: 中国
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Quick Overview for ATRX 抗体 (AA 80-160) (ABIN7223298)

抗原

See all ATRX 抗体
ATRX (helicase 2, X-linked (ATRX))

适用

  • 71
  • 17
  • 4
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  • 2
  • 2
人, 小鼠

宿主

  • 43
  • 30
  • 1

克隆类型

  • 42
  • 32
多克隆

标记

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  • 3
  • 2
  • 2
  • 2
  • 1
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  • 1
This ATRX antibody is un-conjugated

应用范围

  • 30
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  • 9
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ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 8
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    AA 80-160

    原理

    ATRX Polyclonal Antibody

    特异性

    ATRX Polyclonal Antibody detects endogenous levels of ATRX protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human ATRX at AA range: 80-160

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ATRX (helicase 2, X-linked (ATRX))

    别名

    ATRX

    背景

    Rabbit Anti-ATRX Polyclonal Antibody,ATRX, RAD54L, XH2, Transcriptional regulator ATRX, ATP-dependent helicase ATRX, X-linked helicase II, X-linked nuclear protein, XNP, Znf-HX,The protein encoded by ATRX (ATRX, chromatin remodeler) contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in ATRX are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.,Transcriptional regulator ATRX

    基因ID

    546

    UniProt

    P46100
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