HSPB8 抗体
Our Local Distributor
北京 101111
Quick Overview for HSPB8 抗体 (ABIN7212116)
抗原
See all HSPB8 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- HSPB8/HSP22 Monoclonal Antibody
-
纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
-
免疫原
- Recombinant Protein
-
亚型
- IgG1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
-
别名
- HSPB8/HSP22
-
背景
- Mouse Anti-HSPB8/HSP22 Monoclonal Antibody,HSPB8, CRYAC, E2IG1, HSP22, PP1629, Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11, Small stress protein-like protein HSP22,The protein encoded by HSPB8 (heat shock protein family B (small) member 8) belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in HSPB8 have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.,HSPB8
-
分子量
- observerd band 22kDa
-
基因ID
- 26353
-
UniProt
- Q9UJY1
抗原
-