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HAND2 抗体

The 兔 多克隆 anti-HAND2 antibody is suitable to detect HAND2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN7228838
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HAND2 抗体 (ABIN7228838)

抗原

See all HAND2 抗体
HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

适用

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  • 2
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  • 1
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人, 小鼠, 大鼠

宿主

  • 39
  • 4
  • 2

克隆类型

  • 41
  • 4
多克隆

标记

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This HAND2 antibody is un-conjugated

应用范围

  • 36
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Western Blotting (WB), ELISA
  • 原理

    Rabbit Anti-HAND2 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of HAND2 protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human HAND2 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

    别名

    HAND2

    背景

    Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, bHLHa26, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHANDHeart And Neural Crest Derivatives Expressed 2 encoded by HAND2 belongs to the basic helix-loop-helix family of transcription factors. HAND2 product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. HAND2 (Heart And Neural Crest Derivatives Expressed 2) is a Protein Coding gene. Diseases associated with HAND2 include Saethre-Chotzen Syndrome and Split Hand-Foot Malformation. Among its related pathways are NFAT and Cardiac Hypertrophy and Heart Development.

    分子量

    23kD

    基因ID

    9464

    UniProt

    P61296

    途径

    Tube Formation, Feeding Behaviour
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