THRA 抗体 (AA 10-90)
Our Local Distributor
北京 101111
Quick Overview for THRA 抗体 (AA 10-90) (ABIN7224694)
抗原
See all THRA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 10-90
-
原理
- Rabbit Anti-TRα Polyclonal Antibody
-
特异性
- TRα Polyclonal Antibody detects endogenous levels of TRα protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from the N-terminal region of human TRalpha at AA range: 10-90
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- THRA (Thyroid Hormone Receptor, alpha (THRA))
-
别名
- TRalpha
-
背景
- THRA, EAR7, ERBA1, NR1A1, THRA1, THRA2, Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alphaThe protein encoded by THRA (thyroid hormone receptor, alpha) is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
-
分子量
- 55kD
-
基因ID
- 7067
-
UniProt
- P10827
-
途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development
抗原
-