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GRB14 抗体 (AA 50-130)

The 兔 多克隆 anti-GRB14 antibody is suitable to detect GRB14 in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA, WB, IHC 和 IF.
产品编号 ABIN7215152
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GRB14 抗体 (AA 50-130) (ABIN7215152)

抗原

See all GRB14 抗体
GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

适用

  • 33
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  • 1
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  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 33

克隆类型

  • 33
多克隆

标记

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  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
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This GRB14 antibody is un-conjugated

应用范围

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  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-130

    原理

    Rabbit Anti-GRB14 Polyclonal Antibody

    特异性

    GRB14 Polyclonal Antibody detects endogenous levels of GRB14 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the Internal region of human GRB14 at AA range: 50-130

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

    别名

    GRB14

    背景

    GRB14, Growth factor receptor-bound protein 14, GRB14 adapter proteinGrowth factor receptor-bound protein 14 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. GRB14 encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Growth factor receptor-bound protein 14 likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. GRB14 may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.

    分子量

    61kD

    基因ID

    2888

    UniProt

    Q14449
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