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GRAP 抗体 (AA 10-90)

This anti-GRAP antibody is a 兔 多克隆 antibody detecting GRAP in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7219138
发货至: 中国

Quick Overview for GRAP 抗体 (AA 10-90) (ABIN7219138)

抗原

See all GRAP 抗体
GRAP (GRB2-Related Adaptor Protein (GRAP))

适用

  • 19
  • 10
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 18
  • 1

克隆类型

  • 19
多克隆

标记

  • 16
  • 1
  • 1
  • 1
This GRAP antibody is un-conjugated

应用范围

  • 14
  • 9
  • 7
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-90

    原理

    Grap Polyclonal Antibody

    特异性

    Grap Polyclonal Antibody detects endogenous levels of Grap protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human Grap at AA range: 10-90

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    GRAP (GRB2-Related Adaptor Protein (GRAP))

    别名

    Grap

    背景

    Rabbit Anti-Grap Polyclonal Antibody,GRAP, GRB2-related adapter protein,GRAP encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.,GRB2-related adapter protein

    分子量

    observerd band 28kDa

    基因ID

    10750

    UniProt

    Q13588
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