Glutathione Peroxidase 1 抗体
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Quick Overview for Glutathione Peroxidase 1 抗体 (ABIN7228768)
抗原
See all Glutathione Peroxidase 1 (GPX1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GPX1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of GPX1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human GPX1 protein
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亚型
- IgG
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anti-Glutathione Peroxidase 1 (GPX1) (AA 50-203) antibody
GPX1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 164-193), (C-Term) antibodyGPX1 适用: 人, 小鼠, 大鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22987 unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 50-203) antibodyGPX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (Internal Region) antibodyVerified GPX1 适用: 人, Pig WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) antibodyKD Validated GPX1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5600 unconjugated Recombinant Antibody
anti-Glutathione Peroxidase 1 (GPX1) (AA 116-146), (Middle Region) antibodyGPX1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 48-201) antibodyGPX1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 127-193) antibodyGPX1 适用: 人 WB, IHC, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) antibodyKD Validated GPX1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4425 unconjugated Recombinant Antibody
anti-Glutathione Peroxidase 1 (GPX1) (AA 169-199), (C-Term) antibodyGPX1 适用: 人, 小鼠 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Glutathione Peroxidase 1 (GPX1)
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别名
- GPX1
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背景
- Rabbit Anti-GPX1 Polyclonal Antibody,Glutathione peroxidase 1, GPx-1, GSHPx-1, Cellular glutathione peroxidase,Glutathione Peroxidase 1, encoded by GPX1 Gene, belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance, therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. This gene contains an in-frame GCG trinucleotide repeat in the coding region, and three alleles with 4, 5 or 6 repeats have been found in the human population. The allele with 4 GCG repeats has been significantly associated with breast cancer risk in premenopausal women. Alternatively spliced transcript variants have been found for this gene. Pseudogenes of this locus have been identified on chromosomes X and 21.,GPX1
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分子量
- observerd band 22kDa
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基因ID
- 2876
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UniProt
- P07203
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途径
- Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
抗原
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