GRM7 抗体 (AA 320-400)
Quick Overview for GRM7 抗体 (AA 320-400) (ABIN7221374)
抗原
See all GRM7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 320-400
-
原理
- mGluR7 Polyclonal Antibody
-
特异性
- MGluR7 Polyclonal Antibody detects endogenous levels of mGluR7 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the Internal region of human mGluR7 at AA range: 320-400
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
-
别名
- mGluR7
-
背景
- Rabbit Anti-mGluR7 Polyclonal Antibody,GRM7, GPRC1G, MGLUR7, Metabotropic glutamate receptor 7, mGluR7,L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for GRM7.,Metabotropic glutamate receptor 7
-
分子量
- observerd band 102kDa
-
基因ID
- 2917
-
UniProt
- Q14831
-
途径
- Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
抗原
-