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GRM2 抗体 (AA 210-290)

This anti-GRM2 antibody is a 兔 多克隆 antibody detecting GRM2 in ELISA, IF 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7221364
发货至: 中国

Quick Overview for GRM2 抗体 (AA 210-290) (ABIN7221364)

抗原

See all GRM2 抗体
GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This GRM2 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 210-290

    原理

    mGluR2 Polyclonal Antibody

    特异性

    MGluR2 Polyclonal Antibody detects endogenous levels of mGluR2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human mGluR2 at AA range: 210-290

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

    别名

    mGluR2

    背景

    Rabbit Anti-mGluR2 Polyclonal Antibody,GRM2, GPRC1B, MGLUR2, Metabotropic glutamate receptor 2, mGluR2,L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for GRM2.,Metabotropic glutamate receptor 2

    基因ID

    2912

    UniProt

    Q14416

    途径

    cAMP Metabolic Process, Dicarboxylic Acid Transport
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