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GRIA4 抗体

This 兔 多克隆 anti-GRIA4 antibody specifically detects GRIA4 in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7221302
发货至: 中国
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Quick Overview for GRIA4 抗体 (ABIN7221302)

抗原

See all GRIA4 抗体
GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

适用

  • 70
  • 56
  • 33
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 72
  • 2

克隆类型

  • 63
  • 11
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This GRIA4 antibody is un-conjugated

应用范围

  • 61
  • 26
  • 23
  • 13
  • 13
  • 11
  • 9
  • 4
  • 3
  • 3
  • 3
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    GluR4 Polyclonal Antibody

    特异性

    GluR4 Polyclonal Antibody detects endogenous levels of GluR4 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human GluR4 around the non-phosphorylation site of S862

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

    别名

    GluR4

    背景

    Rabbit Anti-GluR4 Polyclonal Antibody,GRIA4, GLUR4, Glutamate receptor 4, GluR-4, GluR4, AMPA-selective glutamate receptor 4, GluR-D, Glutamate receptor ionotropic, AMPA 4, GluA4,Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by GRIA4 belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of GRIA4 show a positive association with schizophrenia.,Glutamate receptor 4

    分子量

    observerd band 100kDa

    基因ID

    2893

    UniProt

    P48058

    途径

    PI3K-Akt Signaling
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