Ghrelin 抗体 (Internal Region)
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Quick Overview for Ghrelin 抗体 (Internal Region) (ABIN7215050)
抗原
See all Ghrelin (GHRL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- Ghrelin Polyclonal Antibody
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特异性
- Ghrelin Polyclonal Antibody detects endogenous levels of Ghrelin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Ghrelin
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亚型
- IgG
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anti-Ghrelin (GHRL) (AA 1-117) antibody
GHRL 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Ghrelin (GHRL) (AA 28-117) antibodyGHRL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) antibodyGHRL 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 25-117) antibodyGHRL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (C-Term) antibodyVerified GHRL 适用: 人, 大鼠 IHC, ELISA, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 31-117) antibodyGHRL 适用: 人, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 1-117) antibodyGHRL 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (C-Term) antibodyGHRL 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ghrelin (GHRL) (AA 1-118) antibodyGHRL 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Ghrelin (GHRL) (Internal Region) antibodyGHRL 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Ghrelin (GHRL)
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别名
- Ghrelin
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背景
- Rabbit Anti-Ghrelin Polyclonal Antibody,GHRL, MTLRP, Appetite-regulating hormone, Growth hormone secretagogue, Growth hormone-releasing peptide, Motilin-related peptide, Protein M46,GHRL encodes the ghrelin-obestatin preproprotein, appetite-regulating hormone, that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for GHRL have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.,Appetite-regulating hormone
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分子量
- observerd band 13kDa
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基因ID
- 51738
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UniProt
- Q9UBU3
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour
抗原
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