GTF2I 抗体 (pTyr248)
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Quick Overview for GTF2I 抗体 (pTyr248) (ABIN7221394)
抗原
See all GTF2I 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr248
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原理
- TFII-I (phospho Tyr248) Polyclonal Antibody
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特异性
- Phospho-TFII-I (Y248) Polyclonal Antibody detects endogenous levels of TFII-I protein only when phosphorylated at Y248.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human TFII-I Phospho-Tyr248
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GTF2I (General Transcription Factor III (GTF2I))
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别名
- TFII-I
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背景
- Rabbit Anti-TFII-I (phospho Tyr248) Polyclonal Antibody,GTF2I, BAP135, WBSCR6, General transcription factor II-I, GTFII-I, TFII-I, Bruton tyrosine kinase-associated protein 135, BAP-135, BTK-associated protein 135, SRF-Phox1-interacting protein, SPIN, Williams-Beuren syndrome chromosomal region,GTF2I encodes a phosphoprotein containing six characteristic repeat motifs. The general transcription factor IIi binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.,General transcription factor II-I
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分子量
- observerd band 115kDa
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基因ID
- 2969
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UniProt
- P78347
抗原
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