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GCSm-gamma (Internal Region) 抗体

The 兔 多克隆 anti-GCSm-gamma antibody (ABIN7215038) specifically detects GCSm-gamma in IHC, ELISA, WB 和 IF. The antibody is reactive with 人, 小鼠, 大鼠 和 猴 samples.
产品编号 ABIN7215038
发货至: 中国
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Quick Overview for GCSm-gamma (Internal Region) 抗体 (ABIN7215038)

抗原

GCSm-gamma

适用

人, 小鼠, 大鼠, 猴

宿主

  • 2

克隆类型

  • 2
多克隆

标记

  • 2
非结合性

应用范围

Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 1
    • 1
    Internal Region

    原理

    Rabbit Anti-GCSm-γ Polyclonal Antibody

    特异性

    GCSm-γ Polyclonal Antibody detects endogenous levels of GCSm-γ protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the Internal region of human GCSm-gamma

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    GCSm-gamma

    背景

    GCLM, GLCLR, Glutamate--cysteine ligase regulatory subunit, GCS light chain, Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, Glutamate--cysteine ligase modifier subunitGlutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    31kD

    基因ID

    2730

    UniProt

    P48507
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