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GCSc-gamma (Internal Region) 抗体

The 兔 多克隆 anti-GCSc-gamma antibody is suitable to detect GCSc-gamma in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA 和 WB.
产品编号 ABIN7215036
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GCSc-gamma (Internal Region) 抗体 (ABIN7215036)

抗原

GCSc-gamma

适用

人, 小鼠, 大鼠

宿主

  • 2

克隆类型

  • 2
多克隆

标记

  • 2
非结合性

应用范围

ELISA, Western Blotting (WB)
  • 抗原表位

    • 1
    • 1
    Internal Region

    原理

    GCSc-γ Polyclonal Antibody

    特异性

    GCSc-γ Polyclonal Antibody detects endogenous levels of GCSc-γ protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human GCSc-gamma

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    GCSc-gamma

    背景

    Rabbit Anti-GCSc-γ Polyclonal Antibody,GCLC, GLCL, GLCLC, Glutamate--cysteine ligase catalytic subunit, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase,Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC encodes Glutamate--cysteine ligase catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at GCLC have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.,Glutamate--cysteine ligase catalytic subunit

    分子量

    observerd band 73kDa

    基因ID

    2729

    UniProt

    P48506
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