GAD65+GAD67 (AA 520-600) 抗体
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Quick Overview for GAD65+GAD67 (AA 520-600) 抗体 (ABIN7214988)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 520-600
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原理
- GAD-65/67 Polyclonal Antibody
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特异性
- GAD-65/67 Polyclonal Antibody detects endogenous levels of GAD-65/67 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human GAD-65/67 at AA range: 520-600
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亚型
- IgG
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anti-GAD65+GAD67 (C-Term) antibody
适用: 小鼠, 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-GAD65+GAD67 (AA 351-450) antibody适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GAD65+GAD67 (C-Term) antibody适用: 小鼠, 人, 大鼠, Cow, 犬, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GAD65+GAD67 (AA 545-594) antibody适用: 小鼠, 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GAD65+GAD67
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别名
- GAD-65/67
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背景
- Rabbit Anti-GAD-65/67 Polyclonal Antibody,GAD1, GAD, GAD67, Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform, GAD2, GAD65, Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65,GAD1 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. Glutamate decarboxylase 1 is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.,Glutamate decarboxylase 1
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分子量
- observerd band 65kDa
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基因ID
- 2571, 2572
抗原
-
