GIT2 抗体 (AA 330-410)
Quick Overview for GIT2 抗体 (AA 330-410) (ABIN7215062)
抗原
See all GIT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 330-410
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原理
- GIT2 Polyclonal Antibody
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特异性
- GIT2 Polyclonal Antibody detects endogenous levels of GIT2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human GIT2 at AA range: 330-410
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亚型
- IgG
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anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibody
GIT2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B5-B9 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal M1 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (Internal Region) antibodyGIT2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-603) antibodyGIT2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (Internal Region) antibodyGIT2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 401-498) antibodyGIT2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 450-510) antibodyGIT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 714-749), (C-Term) antibodyGIT2 适用: 人 WB 宿主: 兔 Polyclonal RB48356 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
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别名
- GIT2
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背景
- Rabbit Anti-GIT2 Polyclonal Antibody,GIT2, KIAA0148, ARF GTPase-activating protein GIT2, ARF GAP GIT2, Cool-interacting tyrosine-phosphorylated protein 2, CAT-2, CAT2, G protein-coupled receptor kinase-interactor 2, GRK-interacting protein 2,GIT2 encodes a member of the GIT protein family, ARF GTPase-activating protein GIT2, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. GIT2 has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. GIT2 undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.,ARF GTPase-activating protein GIT2
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分子量
- observerd band 84kDa
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基因ID
- 9815
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UniProt
- Q14161
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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