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FXYD5 抗体

This anti-FXYD5 antibody is a 兔 多克隆 antibody detecting FXYD5 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7228602
发货至: 中国

Quick Overview for FXYD5 抗体 (ABIN7228602)

抗原

See all FXYD5 抗体
FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))

适用

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宿主

  • 17
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克隆类型

  • 18
  • 1
多克隆

标记

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This FXYD5 antibody is un-conjugated

应用范围

  • 17
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Western Blotting (WB), ELISA
  • 原理

    FXYD5 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of FXYD5 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human FXYD5 protein at AA range: Internal

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))

    别名

    FXYD5

    背景

    Rabbit Anti-FXYD5 Polyclonal Antibody,FXYD domain-containing ion transport regulator 5, Dysadherin,FXYD5 encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin. It also promotes metastasis, and has been linked to a variety of cancers. Alternative splicing results in multiple transcript variants.,FXYD5

    分子量

    observerd band 19kDa

    基因ID

    53827

    UniProt

    Q96DB9
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