FRAT1 抗体 (AA 130-210)
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北京 101111
Quick Overview for FRAT1 抗体 (AA 130-210) (ABIN7228590)
抗原
See all FRAT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-210
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原理
- FRAT1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of FRAT1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human FRAT1 protein at AA range: 130-210
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))
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别名
- FRAT1
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背景
- Rabbit Anti-FRAT1 Polyclonal Antibody,Proto-oncogene FRAT1, Frequently rearranged in advanced T-cell lymphomas 1, FRAT-1,FRAT1 (FRAT1, WNT Signaling Pathway Regulator) is a Protein Coding gene. Among its related pathways are Endometrial cancer and Signaling by Wnt. An important paralog of this gene is FRAT2. The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis.,FRAT1
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分子量
- observerd band 30kDa
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基因ID
- 10023
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UniProt
- Q92837
抗原
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