FOLR2 抗体
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北京 101111
Quick Overview for FOLR2 抗体 (ABIN7228570)
抗原
See all FOLR2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- FOLR2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of FOLR2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human FOLR2 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
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别名
- FOLR2
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背景
- Rabbit Anti-FOLR2 Polyclonal Antibody,Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP,FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. FOLR2 (Folate Receptor Beta) is a Protein Coding gene. Diseases associated with FOLR2 include Neural Tube Defects and Rheumatoid Arthritis. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors.,FOLR2
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分子量
- observerd band 28kDa
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基因ID
- 2350
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UniProt
- P14207
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途径
- Dicarboxylic Acid Transport
抗原
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