Flk-1/Flt-4 (pTyr1054) 抗体
The 兔 多克隆 anti-Flk-1/Flt-4 antibody is suitable to detect Flk-1/Flt-4 in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA, IHC 和 IF.
产品编号 ABIN7222030
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Flk-1/Flt-4 (pTyr1054) 抗体 (ABIN7222030)
抗原
Flk-1/Flt-4
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
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抗原表位
- pTyr1054
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原理
- Rabbit Anti-Flk-1/Flt-4 (phospho Tyr1054/Y1063) Polyclonal Antibody
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特异性
- Phospho-Flk-1/Flt-4 (Y1054/Y1063) Polyclonal Antibody detects endogenous levels of Flk-1/Flt-4 protein only when phosphorylated at Y1054/Y1063.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human Flk-1/Flt-4 Phospho-Tyr1054/Y1063
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Flk-1/Flt-4
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背景
- KDR, FLK1, VEGFR2, Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD antigen CD309, FLT4, VEGFR3, Vascular endothelial growthVEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt-1, KDR/Flk-1, Flt-4, tie-1, and tek/tie-2) whose expression is almost exclusively restricted to the endothelial cells. Tie-1 and tek/tie-2 define a new class of RTKs containing two immunoglobulin-like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt-1, KDR/Flk-1 and Flt-4 are members of the class III subfamily of RTKs containing seven immunoglobulin-like repeats in their extracellular domains. All five RTKs are likely to play central roles in vasculogenesis and angiogenesis.
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基因ID
- 3791, 2324
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UniProt
- P35968, P35916
抗原
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