Filamin A 抗体 (pSer2152)
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Quick Overview for Filamin A 抗体 (pSer2152) (ABIN7213236)
抗原
See all Filamin A (FLNA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer2152
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原理
- Filamin 1 (phospho Ser2152) Polyclonal Antibody
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特异性
- Phospho-Filamin 1 (S2152) Polyclonal Antibody detects endogenous levels of Filamin 1 protein only when phosphorylated at S2152.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Filamin 1 Phospho-Ser2152
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Filamin A (FLNA) (Filamin A, alpha (FLNA))
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别名
- Filamin 1
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背景
- Rabbit Anti-Filamin 1 (phospho Ser2152) Polyclonal Antibody,FLNA, FLN, FLN1, Filamin-A, FLN-A, Actin-binding protein 280, ABP-280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Non-muscle filamin,Filamin A encoded by FLNA is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. Filamin A is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in FLNA are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for FLNA.,Filamin-A
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分子量
- observerd band 280kDa
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基因ID
- 2316
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UniProt
- P21333
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途径
- TCR Signaling, Maintenance of Protein Location
抗原
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