Filaggrin 抗体 (pTyr654)
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Quick Overview for Filaggrin 抗体 (pTyr654) (ABIN7220520)
抗原
See all Filaggrin (FLG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr654
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原理
- Flg (phospho Tyr654) Polyclonal Antibody
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特异性
- Phospho-Flg (Y654) Polyclonal Antibody detects endogenous levels of Flg protein only when phosphorylated at Y654.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Flg Phospho-Tyr654
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亚型
- IgG
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anti-Filaggrin (FLG) (AA 119-336) antibody
FLG 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 998-1104) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FLG-1563 unconjugated
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FLG-1561 unconjugated
anti-Filaggrin (FLG) antibodyFLG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 3838-4061) antibodyFLG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal rFLG-1561 unconjugated Recombinant Antibody
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 兔 Monoclonal FLG-1957R unconjugated Recombinant Antibody
anti-Filaggrin (FLG) (AA 3905-4031) antibodyFLG 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (pTyr654) antibodyFLG 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (pTyr154) antibodyFLG 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Filaggrin (FLG)
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别名
- Flg
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背景
- Rabbit Anti-Flg (phospho Tyr654) Polyclonal Antibody,FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, FGFR-1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD antigen CD331,The fibroblast growth factor receptor 1 encoded by FGFR1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.,Fibroblast growth factor receptor 1
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分子量
- observerd band 120kDa
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基因ID
- 2260
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UniProt
- P11362
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途径
- Sensory Perception of Sound, Stem Cell Maintenance
抗原
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