FGFR1OP 抗体 (AA 310-390)
Quick Overview for FGFR1OP 抗体 (AA 310-390) (ABIN7214926)
抗原
See all FGFR1OP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 310-390
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原理
- FOP Polyclonal Antibody
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特异性
- FOP Polyclonal Antibody detects endogenous levels of FOP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human FOP at AA range: 310-390
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))
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别名
- FOP
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背景
- Rabbit Anti-FOP Polyclonal Antibody,FGFR1OP, FOP, FGFR1 oncogene partner,FGFR1OP encodes a largely hydrophilic centrosomal protein, FGFR1 oncogene partner, that is required for anchoring microtubules to subcellular structures. A t(6,8)(q27,p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.,FGFR1 oncogene partner
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分子量
- observerd band 43kDa
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基因ID
- 11116
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UniProt
- O95684
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途径
- M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
抗原
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