Factor Xa Activated HC (AA 190-270), (Cleaved-Ile235) 抗体
This 兔 多克隆 anti-not_set antibody specifically detects not_set in ELISA 和 WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7220410
发货至:
中国
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Quick Overview for Factor Xa Activated HC (AA 190-270), (Cleaved-Ile235) 抗体 (ABIN7220410)
抗原
Factor Xa Activated HC
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 190-270, Cleaved-Ile235
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原理
- Cleaved-Factor Xa activated HC (I235) Polyclonal Antibody
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特异性
- Cleaved-Factor Xa activated HC (I235) Polyclonal Antibody detects endogenous levels of fragment of activated Factor Xa activated HC protein resulting from cleavage adjacent to I235.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Factor Xa activated HC at AA range: 190-270
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亚型
- IgG
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anti-Factor Xa Activated HC (cleaved), (Ile235) antibody
适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Factor Xa Activated HC
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背景
- Rabbit Anti-Cleaved-Factor Xa activated HC (I235) Polyclonal Antibody,F10, Coagulation factor X, Stuart factor, Stuart-Prower factor,F10 encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.,Coagulation factor X
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分子量
- observerd band 30kDa
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基因ID
- 2159
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UniProt
- P00742
抗原
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