Coagulation Factor X 抗体 (Cleaved-Ala41)
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Quick Overview for Coagulation Factor X 抗体 (Cleaved-Ala41) (ABIN7212514)
抗原
See all Coagulation Factor X (F10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 370-450, Cleaved-Ala41
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原理
- Rabbit Anti-Cleaved-Factor X/ Factor X LC (A41) Polyclonal Antibody
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特异性
- Cleaved-Factor X/ Factor X LC (A41) Polyclonal Antibody detects endogenous levels of fragment of activated Factor X/ Factor X LC protein resulting from cleavage adjacent to A41.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the N-terminal region of human Factor X/ Factor X LC at AA range: 370-450
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亚型
- IgG
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anti-Coagulation Factor X (F10) (AA 21-481) antibody
F10 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (AA 351-381), (C-Term) antibodyF10 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19293 unconjugated
anti-Coagulation Factor X (F10) antibodyF10 适用: 人 ELISA, IHC, IHC (p), IEP, ID 宿主: 绵羊 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (C-Term) antibodyF10 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) antibodyF10 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (AA 235-488) antibodyF10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) antibodyF10 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (AA 351-400) antibodyF10 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (C-Term) antibodyF10 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor X (F10) (AA 21-482) antibodyF10 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Coagulation Factor X (F10)
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别名
- Factor X/ Factor X LC
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背景
- F10, Coagulation factor X, Stuart factor, Stuart-Prower factorF10 encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.
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分子量
- 50kD
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基因ID
- 2159
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UniProt
- P00742
抗原
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