Factor I 抗体 (AA 410-490)
This anti-Factor I antibody is a 兔 多克隆 antibody detecting Factor I in WB 和 ELISA. Suitable for 人.
Quick Overview for Factor I 抗体 (AA 410-490) (ABIN7221664)
抗原
Factor I
适用
人
宿主
兔
克隆类型
多克隆
标记
This Factor I antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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抗原表位
- AA 410-490
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原理
- Factor I Polyclonal Antibody
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特异性
- Factor I Polyclonal Antibody detects endogenous levels of Factor I protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Factor I at AA range: 410-490
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亚型
- IgG
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anti-Factor I (Center) antibody
适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Factor I
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背景
- Rabbit Anti-Factor I Polyclonal Antibody,CFI, IF, Complement factor I, C3B/C4B inactivator,CFI encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene.,Complement factor I
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分子量
- observerd band 66kDa
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基因ID
- 3426
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UniProt
- P05156
抗原
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