Ezrin 抗体 (pTyr146)
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Quick Overview for Ezrin 抗体 (pTyr146) (ABIN7224916)
抗原
See all Ezrin (EZR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr146
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原理
- Ezrin (phospho Tyr146) Polyclonal Antibody
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特异性
- Phospho-Ezrin (Y146) Polyclonal Antibody detects endogenous levels of Ezrin protein only when phosphorylated at Y146.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Ezrin Phospho-Tyr146
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Ezrin (EZR)
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别名
- Ezrin
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背景
- Rabbit Anti-Ezrin (phospho Tyr146) Polyclonal Antibody,EZR, VIL2, Ezrin, Cytovillin, Villin-2, p81,The cytoplasmic peripheral membrane protein encoded by EZR (ezrin) functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for EZR. Alternatively spliced variants have also been described for EZR.,Ezrin
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分子量
- observerd band 69kDa
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基因ID
- 7430
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UniProt
- P15311
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途径
- Maintenance of Protein Location
抗原
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