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ERI1 抗体 (AA 230-310)

This 兔 多克隆 anti-ERI1 antibody specifically detects ERI1 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7225780
发货至: 中国
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Quick Overview for ERI1 抗体 (AA 230-310) (ABIN7225780)

抗原

See all ERI1 抗体
ERI1 (Exoribonuclease 1 (ERI1))

适用

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  • 1
人, 小鼠, 大鼠

宿主

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克隆类型

  • 56
  • 2
多克隆

标记

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This ERI1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 230-310

    原理

    ERI1 Polyclonal Antibody

    特异性

    ERI1 Polyclonal Antibody detects endogenous levels of ERI1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human ERI1 at AA range: 230-310

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ERI1 (Exoribonuclease 1 (ERI1))

    别名

    ERI1

    背景

    Rabbit Anti-ERI1 Polyclonal Antibody,ERI1, 3'EXO, THEX1, 3'-5' exoribonuclease 1, 3'-5' exonuclease ERI1, Eri-1 homolog, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, Protein 3'hExo, HEXO,ERI1, also named as HEXO, 3'HEXO and THEX1, contains one exonuclease domain and one SAP domain. The SAP domain is necessary for binding to the stem-loop structure of histone mRNAs and to form the ternary complex with SLBP, but not for 3'-end histone mRNA exonuclease activity. It is a RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is able to bind other mRNAs. ERI1 is required for 5. S rRNA 3'-end processing. It also binds to 5. s ribosomal RNA. ERI1 binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.,3'-5' exoribonuclease 1

    分子量

    observerd band 37kDa

    基因ID

    90459

    UniProt

    Q8IV48
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