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EIF3A 抗体

The 兔 多克隆 anti-EIF3A antibody (ABIN7228376) specifically detects EIF3A in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7228376
发货至: 中国
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Quick Overview for EIF3A 抗体 (ABIN7228376)

抗原

See all EIF3A 抗体
EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))

适用

  • 47
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  • 25
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  • 4
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  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 46
  • 3

克隆类型

  • 36
  • 13
多克隆

标记

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  • 4
  • 3
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  • 2
  • 2
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  • 2
  • 1
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This EIF3A antibody is un-conjugated

应用范围

  • 37
  • 26
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  • 7
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    Rabbit Anti-EIF3A Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of EIF3A protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human EIF3A protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))

    别名

    EIF3A

    背景

    Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10, eIF-3-theta, eIF3 p167, eIF3 p180, eIF3 p185EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A) is a Protein Coding gene. Diseases associated with EIF3A include Bardet-Biedl Syndrome and Cribriform Carcinoma. Among its related pathways are Viral mRNA Translation and Translational Control. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2: GTP: methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

    分子量

    152kD

    基因ID

    8661

    UniProt

    Q14152

    途径

    Ribonucleoprotein Complex Subunit Organization
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