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ETV1 抗体 (AA 10-90)

This 兔 多克隆 antibody specifically detects ETV1 in WB, ELISA 和 IHC (p). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7214790
发货至: 中国
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Quick Overview for ETV1 抗体 (AA 10-90) (ABIN7214790)

抗原

See all ETV1 抗体
ETV1 (Ets Variant 1 (ETV1))

适用

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  • 5
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  • 1
人, 小鼠

宿主

  • 43
  • 5
  • 1

克隆类型

  • 45
  • 4
多克隆

标记

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This ETV1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 10-90

    原理

    ER81 Polyclonal Antibody

    特异性

    ER81 Polyclonal Antibody detects endogenous levels of ER81 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human ER81 at AA range: 10-90

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ETV1 (Ets Variant 1 (ETV1))

    别名

    ER81

    背景

    Rabbit Anti-ER81 Polyclonal Antibody,ETV1, ER81, ETS translocation variant 1, Ets-related protein 81,ETV1 encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.,ETS translocation variant 1

    分子量

    observerd band 60kDa

    基因ID

    2115

    UniProt

    P50549
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