ESRRG 抗体
Quick Overview for ESRRG 抗体 (ABIN7228436)
抗原
See all ESRRG 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ERR3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of ERR3 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human ERR3 protein
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亚型
- IgG
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anti-Estrogen-Related Receptor gamma (ESRRG) (AA 24-263) antibody
ESRRG 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6G1 unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (Middle Region) antibodyESRRG 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) antibodyESRRG 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) antibodyESRRG 适用: 人 WB, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (Internal Region) antibodyVerified ESRRG 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (N-Term) antibodyESRRG 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 猴, Bat, 小鸡, 非洲爪蟾, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (N-Term) antibodyESRRG 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 猴, Bat, Hamster ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (C-Term) antibodyESRRG 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 猴, 小鸡, Pig, Hamster WB, IHC, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (AA 190-239) antibodyESRRG 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 豚鼠, 猴, Bat, 小鸡, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen-Related Receptor gamma (ESRRG) (AA 24-263) antibodyESRRG 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1D10 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ESRRG (Estrogen-Related Receptor gamma (ESRRG))
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别名
- ERR3
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背景
- Rabbit Anti-ERR3 Polyclonal Antibody,ERR gamma-2, Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3,ESRRG encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors, they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region.,ERR3
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分子量
- observerd band 50kDa
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基因ID
- 2104
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UniProt
- P62508
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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