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ERLIN1/2 抗体 (AA 31-80)

This 兔 多克隆 anti-ERLIN1/2 antibody specifically detects ERLIN1/2 in ELISA 和 WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7226896
发货至: 中国
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Quick Overview for ERLIN1/2 抗体 (AA 31-80) (ABIN7226896)

抗原

ERLIN1/2

适用

人, 小鼠, 大鼠

宿主

  • 8

克隆类型

  • 8
多克隆

标记

  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ERLIN1/2 antibody is un-conjugated

应用范围

ELISA, Western Blotting (WB)
  • 抗原表位

    AA 31-80

    原理

    ERLIN1/2 Polyclonal Antibody

    特异性

    ERLIN1/2 Polyclonal Antibody detects endogenous levels of ERLIN1/2.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from ERLIN1/2 at AA range: 31-80

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ERLIN1/2

    背景

    Rabbit Anti-ERLIN1/2 Polyclonal Antibody,Erlin-1 and erlin-2 (SPFH1 and SPFH2) are SPFH domain-containing proteins that belong to the prohibitin family. The N-termal domain of erlin proteins contains ER-targeting sequences responsible for their translocation to the endoplasmic reticulum (ER). In the ER, erlin-1 and erlin-2 specifically associate with the detergent resistant lipid raft microdomain of the membrane. Erlin-1 may be involved in dentritic cell activation and erlin-2 has been shown to regulate the ER-associated degradation (ERAD) pathway by interacting with endogenous substrates and resulting in their polyubiquitination and degradation.,ERLIN1

    分子量

    observerd band 40+42kDa
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