ERLIN1/2 抗体 (AA 31-80)
This anti-ERLIN1/2 antibody is a 兔 多克隆 antibody detecting ERLIN1/2 in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for ERLIN1/2 抗体 (AA 31-80) (ABIN7226896)
抗原
ERLIN1/2
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This ERLIN1/2 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 31-80
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原理
- ERLIN1/2 Polyclonal Antibody
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特异性
- ERLIN1/2 Polyclonal Antibody detects endogenous levels of ERLIN1/2.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from ERLIN1/2 at AA range: 31-80
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ERLIN1/2
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背景
- Rabbit Anti-ERLIN1/2 Polyclonal Antibody,Erlin-1 and erlin-2 (SPFH1 and SPFH2) are SPFH domain-containing proteins that belong to the prohibitin family. The N-termal domain of erlin proteins contains ER-targeting sequences responsible for their translocation to the endoplasmic reticulum (ER). In the ER, erlin-1 and erlin-2 specifically associate with the detergent resistant lipid raft microdomain of the membrane. Erlin-1 may be involved in dentritic cell activation and erlin-2 has been shown to regulate the ER-associated degradation (ERAD) pathway by interacting with endogenous substrates and resulting in their polyubiquitination and degradation.,ERLIN1
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分子量
- observerd band 40+42kDa
抗原
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