ERD21 抗体
This 兔 多克隆 anti-ERD21 antibody specifically detects ERD21 in ELISA 和 WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7228428
发货至:
中国
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Quick Overview for ERD21 抗体 (ABIN7228428)
抗原
ERD21 (LOC108903962)
(ER Lumen Protein-Retaining Receptor 1-Like (LOC108903962))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This ERD21 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
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原理
- ERD21 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of ERD21 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human ERD21 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ERD21 (LOC108903962) (ER Lumen Protein-Retaining Receptor 1-Like (LOC108903962))
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别名
- ERD21
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背景
- Rabbit Anti-ERD21 Polyclonal Antibody,ER lumen protein-retaining receptor 1, KDEL endoplasmic reticulum protein retention receptor 1, KDEL receptor 1, Putative MAPK-activating protein PM23,Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.,ERD21
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分子量
- observerd band 23kDa
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基因ID
- 10945
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UniProt
- P24390
抗原
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