EPS15 抗体 (pTyr849)
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北京 101111
Quick Overview for EPS15 抗体 (pTyr849) (ABIN7220316)
抗原
See all EPS15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr849
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原理
- Rabbit Anti-Eps15 (phospho Tyr849) Polyclonal Antibody
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特异性
- Phospho-Eps15 (Y849) Polyclonal Antibody detects endogenous levels of Eps15 protein only when phosphorylated at Y849.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human Eps15 Phospho-Tyr849
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
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别名
- Eps15
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背景
- EPS15, AF1P, Epidermal growth factor receptor substrate 15, Protein Eps15, Protein AF-1pEPS15 encodes epidermal growth factor receptor pathway substrate 15 that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, EPS15 is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 100kD
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基因ID
- 2060
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UniProt
- P42566
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途径
- EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation
抗原
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