EMID1 抗体 (AA 690-770)
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Quick Overview for EMID1 抗体 (AA 690-770) (ABIN7227996)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 690-770
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原理
- Rabbit Anti-CO5 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of CO5 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human CO5 protein at AA range: 690-770
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亚型
- IgG
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anti-EMI Domain Containing 1 (EMID1) (AA 54-82), (N-Term) antibody
EMID1 适用: 人 WB 宿主: 兔 Polyclonal RB33492 unconjugated
anti-EMI Domain Containing 1 (EMID1) (C-Term) antibodyEMID1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-EMI Domain Containing 1 (EMID1) (C-Term) antibodyEMID1 适用: 人, 大鼠, 小鼠, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-EMI Domain Containing 1 (EMID1) (C-Term) antibodyEMID1 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- EMID1 (EMI Domain Containing 1 (EMID1))
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别名
- CO5
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背景
- C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4C5 encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in C5 cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
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分子量
- 184kD
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基因ID
- 727
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UniProt
- P01031
抗原
-
