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ELAC2 抗体 (AA 130-210)

This anti-ELAC2 antibody is a 兔 多克隆 antibody detecting ELAC2 in ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN7224036
发货至: 中国

Quick Overview for ELAC2 抗体 (AA 130-210) (ABIN7224036)

抗原

See all ELAC2 抗体
ELAC2 (ElaC Homolog 2 (ELAC2))

适用

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宿主

  • 34
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克隆类型

  • 36
  • 2
多克隆

标记

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This ELAC2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
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    AA 130-210

    原理

    RNase Z2 Polyclonal Antibody

    特异性

    RNase Z2 Polyclonal Antibody detects endogenous levels of RNase Z2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human RNase Z2 at AA range: 130-210

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ELAC2 (ElaC Homolog 2 (ELAC2))

    别名

    RNase Z2

    背景

    Rabbit Anti-RNase Z2 Polyclonal Antibody,ELAC2, HPC2, Zinc phosphodiesterase ELAC protein 2, ElaC homolog protein 2, Heredity prostate cancer protein 2, Ribonuclease Z 2, RNase Z 2, tRNA 3 endonuclease 2, tRNase Z 2,The protein encoded by ELAC2 (elaC ribonuclease Z 2) has a C-terminal domain with tRNA processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in ELAC2 result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for ELAC2.,Zinc phosphodiesterase ELAC protein 2

    基因ID

    60528

    UniProt

    Q9BQ52
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