E2F4/E2F5 (E2F4/5) (AA 30-110) 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠, 大鼠 和 猴.
Quick Overview for E2F4/E2F5 (E2F4/5) (AA 30-110) 抗体 (ABIN7214648)
抗原
See all E2F4/E2F5 (E2F4/5) 抗体
E2F4/E2F5 (E2F4/5)
适用
人, 小鼠, 大鼠, 猴
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 30-110
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原理
- E2F-4/5 Polyclonal Antibody
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特异性
- E2F-4/5 Polyclonal Antibody detects endogenous levels of E2F-4/5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human E2F-4/5 at AA range: 30-110
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亚型
- IgG
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anti-E2F4/E2F5 (E2F4/5) (Internal Region) antibody
E2F4/5 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F4/E2F5 (E2F4/5) antibodyE2F4/5 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- E2F4/E2F5 (E2F4/5)
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别名
- E2F-4/5
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背景
- Rabbit Anti-E2F-4/5 Polyclonal Antibody,E2F4, Transcription factor E2F4, E2F-4, E2F5, Transcription factor E2F5, E2F-5,E2F transcription factor 4 encoded by E2F4 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.,Transcription factor E2F4
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分子量
- observerd band 44kDa
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基因ID
- 1874, 1875
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途径
- Mitotic G1-G1/S Phases
抗原
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