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E2F2 抗体 (AA 190-270)

This anti-E2F2 antibody is a 兔 多克隆 antibody detecting E2F2 in WB, ELISA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7214646
发货至: 中国

Quick Overview for E2F2 抗体 (AA 190-270) (ABIN7214646)

抗原

See all E2F2 抗体
E2F2 (E2F Transcription Factor 2 (E2F2))

适用

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人, 小鼠

宿主

  • 61
  • 7

克隆类型

  • 45
  • 23
多克隆

标记

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This E2F2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 190-270

    原理

    E2F-2 Polyclonal Antibody

    特异性

    E2F-2 Polyclonal Antibody detects endogenous levels of E2F-2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human E2F-2 at AA range: 190-270

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    E2F2 (E2F Transcription Factor 2 (E2F2))

    别名

    E2F-2

    背景

    Rabbit Anti-E2F-2 Polyclonal Antibody,E2F2, Transcription factor E2F2, E2F-2,E2F transcription factor 2 encoded by E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1.,Transcription factor E2F2

    分子量

    observerd band 48kDa

    基因ID

    1870

    UniProt

    Q14209

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
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