Dynamin 1 抗体 (pSer774)
Quick Overview for Dynamin 1 抗体 (pSer774) (ABIN7220058)
抗原
See all Dynamin 1 (DNM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer774
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原理
- Dynamin I (phospho Ser774) Polyclonal Antibody
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特异性
- Phospho-Dynamin I (S774) Polyclonal Antibody detects endogenous levels of Dynamin I protein only when phosphorylated at S774.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Dynamin I Phospho-Ser774
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Dynamin 1 (DNM1)
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别名
- Dynamin I
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背景
- Rabbit Anti-Dynamin I (phospho Ser774) Polyclonal Antibody,DNM1, DNM, Dynamin-1,DNM1 encodes a member of the dynamin subfamily of GTP-binding proteins. Dynamin-1 possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.,Dynamin-1
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分子量
- observerd band 97kDa
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基因ID
- 1759
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UniProt
- Q05193
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途径
- Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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