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DUSP4 抗体

The 兔 多克隆 anti-DUSP4 antibody is suitable to detect DUSP4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN7228316
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DUSP4 抗体 (ABIN7228316)

抗原

See all DUSP4 抗体
DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

适用

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人, 小鼠, 大鼠

宿主

  • 54
  • 4

克隆类型

  • 54
  • 4
多克隆

标记

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This DUSP4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    DUSP4 Polyclonal Antibody

    特异性

    This antibody detects endogenous levels of DUSP4.

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human DUSP4 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

    别名

    DUSP4

    背景

    Rabbit Anti-DUSP4 Polyclonal Antibody,Dual specificity protein phosphatase 4, Dual specificity protein phosphatase hVH2, Mitogen-activated protein kinase phosphatase 2, MAP kinase phosphatase 2, MKP-2,The protein encoded by DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 e product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.,DUSP4

    分子量

    observerd band 44kDa

    基因ID

    1846

    UniProt

    Q13115

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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