MKP-1/2 抗体
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北京 101111
Quick Overview for MKP-1/2 抗体 (ABIN7215770)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-MKP-1/2 Polyclonal Antibody
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特异性
- MKP-1/2 Polyclonal Antibody detects endogenous levels of MKP-1/2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human MKP-1/2 around the non-phosphorylation site of S296/318
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亚型
- IgG
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anti-Dual Specificity Phosphatase 1/4 (DUSP1/4) (Lys92) antibody
DUSP1/4 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1/4 (DUSP1/4) (pSer296), (pSer318) antibodyDUSP1/4 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1/4 (DUSP1/4) (pSer296), (pSer318) antibodyDUSP1/4 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1/4 (DUSP1/4) (AA 261-310), (pSer296) antibodyDUSP1/4 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1/4 (DUSP1/4) (C-Term) antibodyDUSP1/4 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, 斑马鱼 IHC, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- MKP-1/2 (DUSP1/4) (Dual Specificity Phosphatase 1/4 (DUSP1/4))
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别名
- MKP-1/2
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背景
- DUSP1, CL100, MKP1, PTPN10, VH1, Dual specificity protein phosphatase 1, Dual specificity protein phosphatase hVH1, Mitogen-activated protein kinase phosphatase 1, MAP kinase phosphatase 1, MKP-1, Protein-tyrosine phosphatase CL100, DUSP4,Dual specificity protein phosphatase 4 encoded by DUSP14 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
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分子量
- 41kD
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基因ID
- 1843, 1846
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UniProt
- P28562, Q13115
抗原
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