DAPP1 抗体
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北京 101111
Quick Overview for DAPP1 抗体 (ABIN7213762)
抗原
See all DAPP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BAM32 Polyclonal Antibody
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特异性
- BAM32 Polyclonal Antibody detects endogenous levels of BAM32 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human BAM32 around the non-phosphorylation site of Y139
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DAPP1 (Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1))
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别名
- BAM32
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背景
- Rabbit Anti-BAM32 Polyclonal Antibody,DAPP1, BAM32, HSPC066, Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, hDAPP1, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32 kDa,B cell adapter molecule (BAM32) is also designated dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC g2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation. BAM32, which contains one PH domain and one SH2 domain, is primarily expressed in placenta and lung tissues, but can also be detected in heart, liver, pancreas and brain.,Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
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基因ID
- 27071
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UniProt
- Q9UN19
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途径
- BCR Signaling
抗原
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