dTMP Kinase (AA 1-80) 抗体
This 兔 多克隆 antibody specifically detects dTMP Kinase in ELISA, WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7214632
发货至:
中国
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Quick Overview for dTMP Kinase (AA 1-80) 抗体 (ABIN7214632)
抗原
dTMP Kinase
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 1-80
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原理
- dTMP Kinase Polyclonal Antibody
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特异性
- DTMP Kinase Polyclonal Antibody detects endogenous levels of dTMP Kinase protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human dTMP Kinase at AA range: 1-80
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亚型
- IgG
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anti-dTMP Kinase (N-Term) antibody
适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- dTMP Kinase
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背景
- Rabbit Anti-dTMP Kinase Polyclonal Antibody,DTYMK, CDC8, TMPK, TYMK, Thymidylate kinase, dTMP kinase,Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.,Thymidylate kinase
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分子量
- observerd band 22kDa
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基因ID
- 1841
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UniProt
- P23919
抗原
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