DTYMK 抗体 (AA 1-80)
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Quick Overview for DTYMK 抗体 (AA 1-80) (ABIN7214632)
抗原
See all DTYMK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-80
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原理
- Rabbit Anti-dTMP Kinase Polyclonal Antibody
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特异性
- DTMP Kinase Polyclonal Antibody detects endogenous levels of dTMP Kinase protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the N-terminal region of human dTMP Kinase at AA range: 1-80
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亚型
- IgG
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anti-Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK) antibody
KD Validated DTYMK 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5235 unconjugated Recombinant Antibody
anti-Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK) (AA 43-190) antibodyDTYMK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK) antibodyDTYMK 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK) (AA 103-212) antibodyDTYMK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G11 unconjugated
anti-Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK) antibodyDTYMK 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK) (Internal Region) antibodyDTYMK 适用: 人, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK) (AA 1-212) antibodyDTYMK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK) (AA 43-190) antibodyDTYMK 适用: 小鼠 WB, IHC 宿主: 小鼠 Monoclonal C19 unconjugated
anti-Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK) (AA 1-212) antibodyDTYMK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK) (AA 103-212) antibodyDTYMK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- DTYMK (Deoxythymidylate Kinase (Thymidylate Kinase) (DTYMK))
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别名
- dTMP Kinase
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背景
- DTYMK, CDC8, TMPK, TYMK, Thymidylate kinase, dTMP kinaseThymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
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分子量
- 22kD
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基因ID
- 1841
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UniProt
- P23919
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途径
- Nucleotide Phosphorylation
抗原
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