DOK6 抗体 (AA 80-160)
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Quick Overview for DOK6 抗体 (AA 80-160) (ABIN7214610)
抗原
See all DOK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-160
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原理
- Dok-6 Polyclonal Antibody
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特异性
- Dok-6 Polyclonal Antibody detects endogenous levels of Dok-6 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Dok-6 at AA range: 80-160
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DOK6 (Docking Protein 6 (DOK6))
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别名
- Dok-6
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背景
- Rabbit Anti-Dok-6 Polyclonal Antibody,DOK6, DOK5L, Docking protein 6, Downstream of tyrosine kinase 6,The downstream of kinase family (Dok-1-7) are members of a class of "docking" proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.,Docking protein 6
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分子量
- observerd band 43kDa
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基因ID
- 220164
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UniProt
- Q6PKX4
抗原
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