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DOK6 抗体 (AA 80-160)

This 兔 多克隆 anti-DOK6 antibody specifically detects DOK6 in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7214610
发货至: 中国
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Quick Overview for DOK6 抗体 (AA 80-160) (ABIN7214610)

抗原

See all DOK6 抗体
DOK6 (Docking Protein 6 (DOK6))

适用

  • 37
  • 16
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 37

克隆类型

  • 37
多克隆

标记

  • 12
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This DOK6 antibody is un-conjugated

应用范围

  • 25
  • 13
  • 13
  • 12
  • 6
  • 4
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 80-160

    原理

    Dok-6 Polyclonal Antibody

    特异性

    Dok-6 Polyclonal Antibody detects endogenous levels of Dok-6 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human Dok-6 at AA range: 80-160

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    DOK6 (Docking Protein 6 (DOK6))

    别名

    Dok-6

    背景

    Rabbit Anti-Dok-6 Polyclonal Antibody,DOK6, DOK5L, Docking protein 6, Downstream of tyrosine kinase 6,The downstream of kinase family (Dok-1-7) are members of a class of "docking" proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Dok-4, Dok-5 and Dok-6 are more similar to each other than to the other Dok family members, and may constitute a subfamily of the DOK genes. Dok-5 is a tyrosine kinase substrate that enhances c-Ret-dependent activation of mitogen-activated protein kinase (MAPK). Dok-5 transcript is abundant in muscle and increases during T cell activation. Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1. Dok-6 is highly expressed in the developing central nervous system. It associates with Ret to transduce Ret-mediated processes such as axonal projection.,Docking protein 6

    分子量

    observerd band 43kDa

    基因ID

    220164

    UniProt

    Q6PKX4
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