RPA14 抗体 (AA 30-80)
This 兔 多克隆 anti-RPA14 antibody specifically detects RPA14 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7231134
发货至:
中国
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Quick Overview for RPA14 抗体 (AA 30-80) (ABIN7231134)
抗原
RPA14
(DNA-directed RNA polymerase I subunit RPA14 (RPA14))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This RPA14 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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抗原表位
- AA 30-80
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原理
- RPA14 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of RPA14
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human RPA14 protein at AA range: 30-80
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RPA14 (DNA-directed RNA polymerase I subunit RPA14 (RPA14))
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别名
- RPA14
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背景
- Rabbit Anti-RPA14 Polyclonal Antibody,Replication protein A 14 kDa subunit, RP-A p14, Replication factor A protein 3, RF-A protein 3,As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage (PubMed: 9430682). In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. RPA3 (Replication Protein A3) is a Protein Coding gene. Diseases associated with RPA3 include Epidemic Typhus and Ovary Serous Adenocarcinoma. Among its related pathways are Mismatch repair and DNA Double-Strand Break Repair.,RPA14
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分子量
- observerd band 14kDa
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基因ID
- 6119
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UniProt
- P35244
抗原
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